منابع مشابه
Elements and machinery of non-coding RNAs: toward their taxonomy.
Although recent transcriptome analyses have uncovered numerous non-coding RNAs (ncRNAs), their functions remain largely unknown. ncRNAs assemble with proteins and operate as ribonucleoprotein (RNP) machineries, formation of which is thought to be determined by specific fundamental elements embedded in the primary RNA transcripts. Knowledge about the relationships between RNA elements, RNP machi...
متن کاملRevising Predictions
Making a prediction is essentially expressing a belief about the future. It is therefore natural to interpret later predictions as revisions of earlier ones and to investigate the notion of belief revision in this context. We study, both semantically and syntactically, the following principle of minimum revision of prediction: "as long as there are no surprises, that is, as long as what actuall...
متن کاملRevising Concepts
In this paper we present a model for revising concepts using Grove's model for belief revision Gro88]. We model concepts and objects by means of conceptual spaces GG ar98] and show how to deal with prototype eeects. This extends the model presented in Leh98].
متن کاملEfficient production of adenovirus vector lacking genes of virus-associated RNAs that disturb cellular RNAi machinery
First-generation adenovirus vectors (FG AdVs) are widely used in basic studies and gene therapy. However, virus-associated (VA) RNAs that act as small-interference RNAs are indeed transcribed from the vector genome. These VA RNAs can trigger the innate immune response. Moreover, VA RNAs are processed to functional viral miRNAs and disturb the expressions of numerous cellular genes. Therefore, V...
متن کاملMIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis.
Noncoding small RNAs have emerged as important regulators of gene expression at both transcriptional and posttranscriptional levels. Particularly, microRNA (miRNA)-mediated translational repression involving PIWI/Argonaute family proteins has been widely recognized as a novel mechanism of gene regulation. We previously reported that MIWI, a murine PIWI family member, is required for initiating ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BioScience
سال: 1996
ISSN: 0006-3568,1525-3244
DOI: 10.2307/1312944